first_imgSEOUL, South Korea (AP) — South Korean lawmakers say a North Korean diplomat who served as the country’s acting ambassador to Kuwait has defected to the South. The lawmakers say they were told by the National Intelligence Service that the diplomat arrived in South Korea in September 2019 with his wife and at least one child. That would make him one of the most senior North Koreans to defect in recent years. North Korea, which touts itself as a socialist paradise, is extremely sensitive about defections, especially among its elite, and has sometimes insisted that they are South Korean or American plots to undermine its government.last_img read more

first_img This finding could mean that the Capitol area generally was contaminated with anthrax, which fits with certain environmental sampling data, or it could mean that some subjects were exposed to the anthrax envelope before it was opened or had contact with those in groups 1 and 2, the article says. The other three groups, enrolled for comparison, were from outside the Capitol area and consisted of (5) 2 people who had contracted anthrax infections as a result of previous attacks in 2001, (6) 12 with no anthrax exposure, and (7) 7 who were unexposed but had previously been vaccinated against anthrax. Among nonimmunized people, anthrax antibodies were found only in those who were in the building at the time of the attack, mostly in those who were in Daschle’s offices (when tested before vaccination). Anthrax was found in the nasopharyngeal samples of slightly less than half (47.5%) of workers in groups 1 and 2, including all 13 who were in the office where the letter was opened and lesser proportions of those in adjoining offices. None of the people outside the building had positive samples. All the volunteers in groups 1, 2, and 3 (those in the building when the letter was opened) were given antibiotic treatment immediately, and 10 of the 20 people in group 4 (those outside the building but in the vicinity) also opted to take antibiotics. In addition, 51 of the 59 people in groups 1 and 2 received 3 doses of anthrax vaccine starting several weeks after the attack. The postexposure 3-dose vaccination schedule was “highly immunogenic,” given that anti-PA antibodies were found in more than 94% of subjects and CMI responses were seen in more than 86%, the researchers write. In other studies, 99% to 100% seroconversion was seen with a preventive 3-dose schedule. The standard anthrax vaccination schedule, used in the US military, involves 6 doses over 18 months. The researchers studied 124 people, divided into seven groups. The first four groups consisted of (1) 28 people who were in or near Daschle’s office and had positive nasopharyngeal cultures for anthrax, (2) 31 who were in or near the office but had negative cultures, (3) 24 who were elsewhere in the Hart Senate Office Building, and (4) 20 who were outside the building but in the Capitol area (and were presumed to be unexposed). Scientists who prospectively studied people who were in the vicinity when the letter was opened report that even people who were outside the building showed immune responses to anthrax, suggesting that the deadly spores spread more widely than expected. The letter was one of several mailed to two US senators and several media offices in the fall of 2001, resulting in 22 cases of anthrax, 5 of them fatal. Two tests (enzyme-linked immunosorbent assay and fluorescence-activated cell sorting) were used to examine the subjects’ antibody and cell-mediated immune (CMI) responses to two anthrax proteins: protective antigen (PA) and lethal factor (LF). They conclude that antibiotic treatment protected the infected subjects, who were generally young, from becoming clinically ill. “We do not know whether higher exposure could result in clinical disease even with antibiotics or what happens in immunocompromised or immunologically immature populations,” they state. “Despite postexposure prophylaxis with antibiotics, inhalation of B[acillus] anthracis spores resulted in stimulation of the immune system and possibly subclinical infection, and the greater the exposure, the more complete the immune response,” says the report by Denise L. Doolan of the Naval Medical Research Center in Silver Spring, Md., and associates from there and several other institutions. “Our data demonstrate that exposure to B. anthracis spores primed antibody and cellular responses in a dose-dependent and antigen-specific manner in immunized and unimmunized subjects, enhanced AVA-boost responses, and boosted recall responses in previously immunized subjects,” the researchers write.center_img No significant differences in symptoms were seen between subjects with and without anthrax exposure and with and without immune responses, except for headache, which was more common in exposed people but correlated with the duration of antibiotic use. Jan 10, 2007 (CIDRAP News) – The anthrax-laced letter sent to Sen. Tom Daschle’s office in 2001 may have affected more people than was recognized at the time, but the antibiotics and vaccinations given to potentially exposed people were highly effective, according to an immunologic study of the event. See also: The researchers, writing in the Journal of Infectious Diseases, also report that those who were exposed showed immune responses to anthrax even though they were immediately put on preventive antibiotic treatment. Further, they found that 3 doses of anthrax vaccine adsorbed (AVA)—versus the standard 6-dose regimen—triggered a strong immune response in those who were vaccinated after the attack. The researchers also report an inverse relationship between CMI responses and antibiotic treatment, which suggested that the treatment impeded anthrax spore germination, the report says. In the previously vaccinated volunteers—who were revaccinated during the study—immune responses were strong even after a single new dose of vaccine. Doolan DL, Freilich DA, Brice GT, et al. The US Capitol bioterrorism anthrax exposures: clinical epidemiological and immunological characteristics. J Infect Dis 2007 Jan 15;195(2):174-84 [Full text] In the tests for CMI, the researchers found a direct relationship between presumed anthrax exposure and response rate. Unexpectedly, however, they found evidence of CMI in some people who were outside the building (group 4). For example, monocytic responses were detected in more than 70% of groups 1 and 2, 37.5% of group 3, and 30% of group 4. Monocytic responses for group 4 were significantly higher than those for unexposed controls (group 6). Hadler JL. Learning from the 2001 anthrax attacks: immunological characteristics. (Editorial) J Infect Dis 2007 Jan 15;195(2):163-4 [Full text] The data suggest, they add, that low-level anthrax exposure induces asymptomatic cellular immune responses without antibodies and that intermediate exposure induces both cellular and antibody responses.last_img read more

first_imgLetterkenny Town Councillor Jimmy Kavanagh has called on the council to update the derelict sites register for the town and to set about enforcing the terms of the derelict sites act, in an effort to rid the town of derelict buildings and sites.Under the Derelict Sites Act, the owners of urban land or property listed on the derelict sites register must pay an annual levy to their local authority of three percent of the market value of their property; this can subsequently rise to a maximum of ten percent.Cllr Kavanagh now wants a survey of the Letterkenny Town Council area and an upgrade of the derelict sites register and to adopt a policy of zero tolerance in the enforcement of the levies payable under the Act. “Derelict sites and boarded up houses give a bad impression, they are a magnet for anti social behaviour, they lower the value of the houses around them, and they undermine the magnificent work being done by the tidy towns committee.“In a number of instances the owners of derelict houses in the town live far away from them and seem to care little that their properties are an eyesore, these owners are also well removed from the anti social behaviour that their boarded up houses attract.“In other cases the owners are banks and other state agencies, and I feel that if the penalties under the Act were strictly enforced that these particular owners would be compelled to deal with the problem much more quickly.” Kavanagh concluded.  ZERO TOLERANCE NEEDED ON DERELICT HOUSES AND SITES – KAVANAGH was last modified: October 9th, 2012 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:Cllr Jimmy Kavanaghderelict siteslast_img read more